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Biotechnology

Department of Biotechnology

Biotechnology is an applied Science which offers an amalgamation of Technology with the Biological sciences like Microbiology, Biochemistry, Genetics, Molecular Biology, Immunology, Cell Biology and Cytogenetics. The scope of Biotechnology is wide and it’s applications are diverse and multidisciplinary. Along with conventional (and indispensible) techniques like fermentation, it also encompasses modern subjects like Bioinformatics, Proteomics, Genomics, Animal Tissue culture, Plant Tissue culture, Nanobiotechnology, Gene Therapy, Genetic Counseling, Developmental biology, Neurobiology, Endocrinology, Genetic Engineering to name a few.

Biotechnology has great impact on all domains of human life. Advancement in the field of Biotechnology has revolutionized many industrial processes and research approach. It has great impact on latest trends in research and development in Health sector, Pharmaceuticals, Diagnostics, Food Technology, Agricultural trends, Environmental conservation. In general, Biotechnology has largely contributed towards improvement of Quality of human life.

History

The Department of Biotechnology at Jai Hind College was established in the academic year 2002-2003. Now, for over a decade and a half the Department of Biotechnology at Jai Hind College continues to be one of the most sought after for Biotechnology in Mumbai. Since it’s inception it has offered comprehensive knowledge with an opportunity to excel and hence cater to young talent through academic activities and research platforms.

The Department of Biotechnology at Jai Hind College, under the flagship of Autonomy, offers a stand-alone course in Biotechnology. Students learn through a carefully designed syllabus which is updated on regular basis with an aim to impart knowledge, understanding, skills and application oriented approach amongst young minds. Innovative and interactive teaching methods offered here have made the whole process of learning very interesting and engaging for students. The department offers amicable learning environment under the guidance of highly experienced faculty.

Departmental Features

  • A Large and well equipped Laboratory for undergraduate practical.
  • Plant tissue culture laboratory with Laminar air flow cabinet.
  • Departmental library.
  • Teachers have received recognition for M.Sc in Biotechnology.
  • Teachers have completed minor research projects funded by Mumbai University and UGC
  • Teachers actively involved in guiding students for research projects
  • Many students have won prizes at Inter collegiate Research meets

Best Practices of the Department

  • Well qualified and experienced staff
  • Trained nonteaching staff
  • Innovative teaching methods
  • Use of LCD, animations, E learning tools
  • Interactive learning environment
  • Discussion clubs, tutorials
  • Encourage students to share latest developments in the field
  • Guidance rendered to students for research projects, and subsequent presentation and publication
  • Conduct Regular Class test using novel assessment methods like infographics, dramatics, quiz sessions, report writing
  • Take extra lectures for topics difficult to grasp and understand
  • Staff meeting on regular basis to discuss various matters of the department
  • Parent teacher meeting
  • Encourage and help students for extracurricular activities

Industrial/ Institutional/ Nature park Visits

In order to enhance the understanding of the concepts taught, the Department of biotechnology organizes annual visits to various Biotechnology based research institutes and industries. The visits are planned within the city as well as outstations. These visits have certainly broadened the horizon of understanding the scope of the subjects amongst students. Following are few places of interest visited by the students of Jai Hind College, Biotechnology.

  • Biocon : Banglore
  • Wockhardt : Aurangabad
  • NCBS : Banglore
  • CCMB : Hyderabad
  • NDDB: Anand , Gujarat
  • Amul - Anand
  • NCCS- Pune
  • Serum Institue of India - Pune
  • ICGEB-Delhi
  • IIT, Delhi
  • National Institute of Immunology: Delhi
  • CPRI-Shimla
  • NBPGR-Shimla
  • Mushroom Factory and Medicine factory, Baddi : H.P
  • National institute of Ocenography, Panaji : Goa
  • Tulip Group of Companies: Goa
  • Coca Cola: Goa
  • UB Group: Goa
  • Institute for Genetics : Hyderabad
  • Mother Dairy : Hyderabad
  • United Spirits : Hyderabad
  • Sula Vineyards : Nashik
  • ACTREC : Navi Mumbai (Annual Open-Day)
  • SGNP, Mumbai

Strengths

  • One of the high in-demand subjects in the field of Science.
  • Academic excellence shown every year with high number of distinctions and top ranks at University.
  • Many students pursue masters and doctoral degrees, few also pursue postdoctoral studies.
  • Very well placed alumni
  • Organization of a successful intercollegiate festival- Genaces for over last 10 years.
  • Annual Visits to Institutions of academic excellence and Industries of Biotechnology.
  • Organization of seminars/ workshops has been a regular feature of the Department of Biotechnology.
  • “Techniques and Advances in Immunology” – Teacher’s training workshop organized in collaboration with Lady Tata Memorial Trust.

Internships

The Department of Biotechnology at Jai Hind College provides excellent learning environment for our students through Class room teaching, Laboratory work and summer training. We encourage motivate our FY, SY and TY students to undertake internships at various industries, hospitals, Research centers & laboratories to get an insight in the practical application of their theoretical knowledge. Few Institutions where students are pursue their Summer Training:

  • Bhatia hospital
  • Bombay hospital
  • NMIMS School of Biological Sciences
  • Jaslok Hospital & Research Center
  • Haffkins Institute
  • C B Patel Research centre
  • NCBS Bangalore
  • KEM Hospital
  • ACTREC
  • P.H.Medical
  • Biocon, Bangalore
  • Nature Magazine, London

The scope of Biotechnology is wide and diverse. Our students have built incredible careers in industry, academia and in research sectors alike. Alumni of Jai Hind Biotechnology are is very well placed in sectors like Food and Beverages industry, Brewery/ winery, FMCG, environmental sectors.

We at the department are extremely pleased with the achievements of our students. Our students have qualified competitive entrance exams for Masters program and have secured admissions at institutes of great national and international repute.

  • University of Mumbai
  • M.S. University Baroda
  • ACTREC Panvel
  • NIRRH, Mumbai
  • TIFR, Mumbai
  • IISER, Pune
  • IISER, TVM
  • NCBS, Bangalore
  • TCIS, Hyderabad
  • IIT, Delhi
  • NII, Delhi
  • McGill University, Canada
  • John Hopkins, USA
  • NIH, Washington
  • University of Singapore
  • Northeastern University, USA
  • University of Pennsylvania, USA
  • University of Massachusetts, USA
  • Columbia university, USA

Placement Record of students

Biotechnology provides great employment opportunities in diverse sectors. Our students are very well placed in academia, research, industry and in entrepreneurial endeavors alike.

They hold various offices ranging from Academicians, Research Associates, Scientific Officers, QA/ QC managers, Scientific Editors, Clinical Research Associates, Bioinformaticians, Science journalists, Scientific Reporters, Project and Production Administrators and Managers.

  • Research Associate in NYU Medical Centre, New York
  • Marketing Manager at Zuventus, Department of Oncology
  • Ph. D. and Job in USA/ UK/ Australia/ Singapore/ Canada
  • Quality assurance/ Quality control
  • Regulatory affairs
  • Law firms
  • Manager Marketing Life Cell
  • Nature Magazine- Junior editor
  • Floor Manager at 3G.
  • Lecturer in Biotechnology in Colleges of repute
  • Voice and Accent Trainer In JP Morgan
  • Research Officer in Bharat Serum and Vaccines
  • PR Consultant for Genesis Burson Marsteller.
  • Ph.D. in Biomedical Sciences, University of Toledo
  • Project Manager in a reputed Pharmaceutical firm
  • Manager in Varda Biotech
  • Investment Banker in ICICI Bank
  • Medical Underwriter in ICICI Prudential
  • Working for CPC Diagnostics
  • Manager, Sula wines
  • Entrepreneur

Department Festival

Genaces - Intercollegiate Biotechnology Festival of the Department of Biotechnology Jai Hind College. Brainchild of the S.Y. B.Sc. students of the 2007 -2008 batch, Genaces was started with the aim of inculcating the spirit of team work and enhancing management skills. This annual festival is organized by the students under the guidance of faculty. Through organization of various events and competitions at Gences, students develop numerous soft skills. Genaces provides a great platform to showcase the leadership qualities, management skills and creativity of students.

Department Activities and student achievements; some glimpses

Faculty

Faculty Profile: TEACHING STAFF


Name of the Members

Designation

Qualification

Dr. Kruti Pandya

Joint-Coordinator

Ph.D. Biochemistry M.Sc., Biochemistry, SET, BE.d,

Dr. Nissey Sunil

Joint-Coordinator

Ph.D. Bioanalytical Sciences, NET

Dr. Hiral Pandya

Assistant Professor

Ph.D. Biotechnology, NET

Dr. Monalisa Chakraborty

Assistant Professor

Ph.D. Biotechnology, RET

Faculty Profile: NON TEACHING STAFF


Name of the Members

Designation

Qualification

Ms. Deepali Surve

Laboratory Assistant

B. Sc Biotechnology

Mr. Rohit Kadam

Laboratory Attendant

B. A

 

Syllabus

Research

Dr. Kruti Pandya

Research Publications:

  • Pandya K. and Phadke M.S. Oct-Dec 2012. Isolation and characterization of lipase producing bacteria from spoiled fruits and vegetables. International journal of Biotechnology and Biosciencses. (Peer reviewed, quarterly published)ISSN NO-2231-0304, 2(4), Page no - 306-312.
  • Pandya K. and Phadke M.S. April-June 2013. Partial purification and process optimization of bacterial lipases. International Journal of Environmental Sciences. (Peer reviewed Quarterly published) ISSN NO-2249-2127. 2(2), Page no; 80-84.
  • Pandya K, Zaveri M., Kanojia N., and Sidpurwala U. April – June 2014. Study of industrial applications of bacterial exoprotease. International Journal of Biotechnology and Biosciences. (Peer reviewed quarterly published) ISSN NO - 2231-0304.
  • Pandya K. Lakdawala A., Jones M., Kotwal U. July-Sept 2014. Invitro biodegradation of cat hair by bacterial keratinase. International Journal of Environmental Sciences. (Peer reviewed Quarterly published) ISSN NO-2249-2127. (This project was selected in round 2 at Avishkar- Interuniversity research meet)
  • Pandya K. and Phadke M. S. MAY 2015. Analysis of diesel biodegradation using gas chromatography mass spectroscopy (GCMS). Bionanofrontier: Journal of science and Technology: Volume (8), 3, 67-70; (Peer Reviewed) ISSN 0974-0678.E journal: Print ISSN:0974-0678,Online:2320-9593, SJIF impact factor-4.856.
  • Pandya K., Naik A., Singh A. Oct 2016. Comparative study of buffering capacity of an innovative cymbopogan flavoured herbal mouth wash against commercial chemical mouth wash in oral health. International Journal of Pharma Drugs Analysis.ISSN-2348-8948. 10,(4)., 480-485. SJIF impact factor- 4.1
  • Mansawala R. M., Shiza S., Pandya K. Dec, 2016 Preliminary study and characterization of a prodigiosin producing soil bacteria and applications of biopigment in natural cosmetics. International J of Current Advanced Research. ISSN-2319-6475(E) 2319-6505(P. 5(12)544-1547.).
    • SJIF impact factor- 4.915

Research Projects

  • Dr. Kruti Pandya. BCUD Minor Research Project Completed 2012-13- Isolation and study of microbial lipases from oil spill areas around Mumbai
  • Dr. Kruti Pandya. UGC Minor Research Project Sanctioned 2015- PCR based gene sequencing for a Triacylglycerol esterase

Scientific Poster Presentation:

  • Pandya Kruti and Phadke Madhavi. Insilico Analysis and identification of lipase producing acidophilic bacteria from waste disposal site in Central Mumbai suburb (NMIMS, NOV, 2013)
  • Pandya Kruti and Phadke Madhavi. Partial purification, immobilization and insilico analysis of bacterial lipase (Konark research meet, SIES, DEC, 2013
  • Pandya Kruti and Phadke Madhavi. Study of Industrial Applications of bacterial lipases. (AVISHKAR, Kalina, January, 2014)

Gene Sequence Submission to NCBI:

Dr. Nissey Sunil.

Research Paper Publication

  • N Sunil, J D Vora. 2015. Characterization of indigenous lactic acid bacteria and survival studies in response to acid and bile stress. International Journal of Food and Nutritional Sciences 4:83-85.
  • N Sunil, J D Vora. 2016. Analysis of 16S rRNA gene of lactic acid bacteria isolated from curd and raw milk. International Journal of Science and Research 5(5): 1806-08.
  • N Sunil, J D Vora. 2018. Probiotics – Role in health and wellbeing. International Journal of Scientific Research and Review 7(11). ISSN: 2279-543X.
  • Resmi K R, Nissey V, Krishnan L K. 2004. Procedure for quantification of platelet adhesion to biomaterials by radioscintigraphy. Thrombosis Research; 114(2):121-8.
  • Krishnan L K, Nissey V, Muraleedharan C V, Bhuvaneshwar G S, Derangere F, Sampeur Y, Suryanarayanan R. 2002. Quantitation of platelet adhesion to Ti and DLC-coated Ti in vitro using I125-labeled platelets. Biomolecular Engineering; 19(2-6):251-3.
Research Projects
  • Dr. Nissey sunil. UGC – Minor Research Project “Isolation and identification of indigenous strains of lactic acid bacteria having probiotic potential”

Scientific Poster Presentation:

  • Nissey V, Bhuvaneshwar G S, Krishnan L K. Use of 125I-labeled platelets for quantitation of platelet adhesion to biomaterials in vitro using phosphor imaging. (NUCAR 2001)

Dr. Hiral Pandya.

Research Paper Publication

  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali November, 2017 Enhanced acidogenesis by degenerated Clostridium sp. strain on continuous membrane cell recycle reactor. Advances in Biotechnology and Microbiology. ISSN 2474-7637. 7(4): 555716. DOI: 10.19080/AIBM.2017.07.555716.

Poster/Oral Presentations

  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali November, 2015. Enhanced organic acid production using Clostridium acetobutylicum ATCC 4259 with improved process economics (poster). International Conference on New Horizons in Biotechnology (NHBT-2015) at NIIST, Thiruvananthapuram, Kerala 695019, India
  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali December, 2014. Optimization of conditions for complete substrate utilization by Clostridium acetobutylicum ATCC 4259 (oral). Bioprocessing India, 2014, jointly organized by ICT, Matunga, Mumbai and IITB, Mumbai, India.*
  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali September, 2014. Study of Lactic acid production and reutilization for maximum butyric acid production by degenerated strain of Clostridium acetobutylicum ATCC 4259 (poster). Clostridium XIII, 13th International conference on the genetics, physiology and synthetic biology of solvent and acid forming clostridia at Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Shanghai, China.**
  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali November, 2012 Fermentative butyric acid production by Clostridium spp. (poster). 53rd AMI International Conference “Microbial World: Recent Innovations and Future trends” at KIIT, Bhubaneshwar, Odisha, India.
  • Hiral S, Abhishek M, Aruna GA, Annamma AO and Arvind Lali January, 2011 Insights and development in Butanol fermentation (poster). YRC-YICC, 2011 at ICT, Mumbai, India.

Fellowships and Awards

  • Qualified for Junior Research Fellowship followed by Senior research fellowship by University Grant Commissions (UGC), Government of India. (January, 2011-December, 2015) for doctoral research work
  • Awarded the Young Scientist in Bioprocessing in the category of Bioengineering and Fermentation at Bioprocessing India 2014, held at Institute of Chemical Technology Mumbai, India, December 17th-20th, 2014
  • International Travel grant sponsored by ICMR, Government of India, for presentation at Clostridium XIII, 13th International conference on the genetics, physiology and synthetic biology of solvent and acid forming clostridia held at Shanghai Hope Hotel, Shanghai 200031, China (Dapuqiao), September 19th‐21st, 2014.

Organism Deposition

Deposited an organism Bacillus sp. T8(2011b) GenBank: JN885459.1 ( http://www.ncbi.nlm.nih.gov/nuccore/JN885459.1)

Dr. Monalisa Chakraborty

Research Publications

  • Chakraborty M, Bagchi B, Das S, Basu R, Nandy P. 2018 . Study the dose dependant insulin secretagogues action of eucalyptus oil & its Hepatoprotective and Nephroprotective activity on Streptozotocin induced diabetic mice model."Springer: Clinical Phytoscience.(Peer reviewed) ISSN: 2199-1197, 4, Page no.-1-10.
  • Chakraborty M, Kar S, Das S, Basu R, Nandy P. 2017. A pharmacological aspect of nanomedicine Cuprum metallicum on rapid wound healing activity: An in vivo approach."American Journal of Homeopathy Medicine. (Peer reviewed)ISSN: ISSN. 1934-2454,110(3), Page no-14-17.
  • Chakraborty M, Dey A, Bala N, Das S, Basu R, Nandy P. 2015. Rapid single step greensynthesis of copper oxide nanoparticles from Vigna radiata using three copper salts and study its antimicrobial nature."International Journal of pharmacy.(Peer reviewed) ISSN : 2249-1848; 5(1) , Page no.- 93-97.
  • Chakraborty M, Das S, Basu R, Nandy P. 2015. Study of the Altered Anisotropy of Erythrocyte Ghost Membrane upon Interaction with Phytoreduced Negatively Charged Gold Nanoparticle from Celosia cristata and Vigna radiata."American Journal of Nanoscience and Nanotechnology Research (Peer reviewed), ISSN 2574-2651 ,3(1): Page no.-1-11.
  • Chakraborty M, Ghosh S, Das S, Basu R, Nandy P. 2015. Effect of Different Potencies of Nanomedicine Aconitum Napelles on Its Spectral and Antibacterial Properties."International Journal of Innovative Research in Science, Engineering and Technology. (Peer reviewed ) ISSN: 2347-6710, 4(8), Page no.- 6861-6867.
  • Chakraborty M, Das S, Manchanda K.R ,Basu R, Nandy P.2015 .Application of nanomedicine Cuprum metallicum as an agent for remediation of an azo dye, methyl orange and study its associated antimicrobial activity."International Journal of Environmental Sciences.(Peer reviewed quarterly). ISSN:0976-4402, 6(3) Page no.-345-351.
  • Bala N, Saha S, Chakraborty M, Maiti M, Das S, Basu R and Nandy P. 2015.Green synthesis of zinc oxide nanoparticles using Hibiscus subdariffa leaf extract: effect of temperature on synthesis, anti-bacterial activity and anti-diabetic activity."RSC Advances.( Peer reviewed). ISSN: 2046-20695, Page no.- 49935003.
  • Ghosh S, Chakraborty M, Das S, Basu R, Nandy P. 2014.Effect of Different Potencies of Nanomedicine Cuprum metallicum on Membrane Fluidity-a Biophysical Study."American Journal of Homeopathy Medicine. ( Peer reviewed) ISSN : 1934-2454, 107(4), Page no.-161-169.
  • Kar S, Bandyopadhyay P, Chakraborty S, Chakraborty M, Paul .B, Ghosh S, Basu R, Das S, Bhar S.D, Manchanda R, Khurana A, Nayak D, Nandy P. 2015. Derivation of anempirical relation between the size of the nanoparticle and the potency of homeopathic medicines."International Journal of High Dilution Research.(Peer Reviewed) ISSN:1982-6206, 14 (4), Page no.-2-7.
  • Kar S, Chakraborty M, Nandy P, Basu R, Das S, Bhar S D, Manchanda K R, Khurana A, Nayak D. 2017 Characterization and haemocompatibility of Aurum metallicum for its potential therapeutic application."Indian Journal of Research in Homeopathy.(Peer reviewed). ISSN: 0974-7168,11(1), Page no.- 41-47.
  • Bera D, Chakraborty M, Paul K. B, Bandhyopadhyay P, Das Sukhen, Bardhan S, Bhar S. D, Nandy P. 2017. Antibacterial activity of Silicea, Calc carb ,Sulphur on gram negative bacteria E.coli."International Journal of Current Medical and Pharmaceutical Research.(Peer reviewed) ISSN: 2395-6429 ; 3(12), Page no- 2774-2777.
  • Koner A, Chakraborty M, Nandi N, Chowdhury P, Chakraborty S. 2012 Detoxification of Homeopathic Potency using Eukaryotic System."World Journal of Science and Technology. ISSN: 2231 2587, 2(7).

Books Published

  • P. Nandy, P. Bandyopadhyay, M. Chakraborty, A. Dey, D. Bera, B. K. Paul, S. Kar, A. Gayen, R. Basu, S. Das, D. S. Bhar, R. K. Manchanda, A.K. Khurana, D. Nayak. 2018. Chapter: Homeopathic Nanomedicines and Their Effect on the Environment. Handbook on Modern Environmental Materials Management, Springer International Publishing Print, ISBN-978-3-319-73644-0 (2018).
  • B.K.Paul, P. Bandyopadhyay, S. Ghosh, M.Chakraborty, S. Kar, A.L. Gayen, D. Bera, D.Mondal, A.K. Singh, R. Basu, S. Das, D.S. Bhar, P. Nandy. 2019. Chapter: Evidences of Nano-particle aspect of homeopathic medicine. Recent Trends in Materials Physics and Chemistry. Stadium Press (India) Private limited. ISBN – 9789385046322

Reviewer: Clinical phytoscience springer 2019, March

Research Projects:

  • Developing the fastest, low cost easy methods of synthesizing pharmacologically active nano-particles and understanding the role of metabolites as therapeutics.
  • Study the nanoparticle (drug) interaction with the artificial lipid membrane (DPPC) and erythrocyte ghost cell membrane by analyzing the membrane anisotropy and change of phase transition temperature, motionally restricted lipid molecule, Van't Hoff Enthalpy. Also calculated the percentage hemolysis to ensure drug hemocompatibility.
  • Triturated drug Cuprum metallicum adsorbed in MMT (Montmorillonite) clay used as a therapeutic agent for treating artificial wound in animal model.
  • Dose dependant study of insulin secretagogues action of Eucalyptus essential oil from Eucalyptus globulus and analyze the hepatoprotective & nephroprotective activity on induced diabetic mice model with the help of biochemical and histopathological assay. Comparative study of parameters including body weight, blood glucose and other serum enzymes of liver, kidney and pancreas and change of cell morphology(Histology) before induction and after induction of diabetes and after treated with different dose of plant extract was done.

Professional Presentations

  • Phytoreduction of copper oxide nanoparticles from Vigna radiata and its antibacterial activity,"2017 at National symposium on Nanotechnology; From materials to Medicines and their social impact organized by Centre for interdisciplinary Research and Education, Birla Industrial and Technological Museum, West Bengal University of Technology, Adamas University Kolkata, India (Poster Presentation).
  • Application of nanomedicine Cuprum metallicum as an agent for remediation of an azo dye, methyl orange and also study its antimicrobial properties,"2016 at National conference on science behind homeopathy. Center for Interdisciplinary Research and Education, Birla Industrial and Technological Museum, Kolkata, India (Poster Presentation).
  • A green approach towards nanotechnology,"2015 at International Conference on Frontiers in Biological Sciences. National Institute of Technology, Rourkela, Odisha, India (Poster Presentation).
  • A Pharmacological aspect of nanomedicine Cuprum metallicum on rapid wound healing activity: An in vivo approach,"2015 at Condensed Matter Physics Research Centre. Jadavpur University, Jadavpur, Kolkata, India. (Poster Presentation).
  • Effect of Different Potencies of Nanomedicine Cuprum metallicum on Membrane Fluidity-a Biophysical Study,"2013 at National conference on photosciences: Contemporary Challenges and Future Prospectives. Indian Photobiological society, Jadavpur University, Jadavpur, Kolkata, India (Poster Presentation).
  • Recent trends in Biotechnology,"2010 at National seminar on recent trends in Biotechnology.Department of Biotechnology, University of Burdwan, Burdwan, India (Poster Presentation).